Sure, some B, HD, T and K bikes might obtain high mileage but that is unusual. So many Y, S and H bikes do it as to be almost routine. There are always deviations from statistical averages, but the bell curve says you have a better chance buying a Tenere or a Vstrom, changing the oil and riding the beast till you get tired of it, not till it has an expensive mechanical issue.
My 2001 HD Road King coughed up a cam chain tensioner shoe at 25,000 miles, had I not found it first it would have taken out the oil pump and blown up the engine. It was still a bunch of money to replace the chains, bearings and timing tensioner shoes. Then a year later the same bike had a ring stick in the grove of a piston due to excess cylinder heat (my opinion) and I had to top end the machine to the tune of almost a $1000 with me doing most of the labor.
Two of my four BMW buddies have done the ABS brake failure on one GS and the final drive on both. ::021::