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There may be nothing wrong with the bike, though the handle bar weights do seriously impact bar vibes. Maybe the previous owner had some kind of BarkBusters installed? Can you share a pic of the end of your bar. It is unusual for the weights to be missing. Do you have handguards?
Yamaha tends to put bars on that have a lot of 'sweep'. This means the bars are angled back toward the bike from what would be considered a strait line across the risers.
Sit on the bike and put your hands lightly on top of the grips w/o gripping the bars in a position that is natural for you. Do you have to rotate your wrists to then grip the bars?
On some bikes a small change in sweep can make a huge difference in comfort and eliminating numbness like that you describe. Something more neutral for you would help.
Grip buddies or puppies give you a large diameter grip and do absorb some vibes. A cheap thing to try before considering bar replacement. The cramp buster/throttle rocker allows you to use your palm to rotate the throttle so you don't have to grip the throttle as tightly. Again, an inexpensive thing to try. Some don't care for them, and it takes a little getting used to. If it's in the wrong position, it can lead to unexpected/unintended acceleration when going for the brake quickly. Most people adapt quickly to using it.
Seat - I'm going to guess you weight more than 150 lbs. A lot of riders over that find the stock seat to be a little soft. Combined with a new riding position, this can result in a sore butt.
What bike did you have before, or are accustomed to riding if you still have it? (I'm asking so we know what riding position you were used to.)
This is something you may simply get used to if your riding position has changed from the previous bike. You can spend a lot of money trying relatively inexpensive products like sheep skin covers, bead covers, AirHawk inflatable pads, Gel pads, etc. Or you can bite the bullet and spend a bunch of money once on a custom seat. Not an off the shelf aftermarket seat. That's really hit or miss and as expensive or more than a true custom seat. But a custom seat does not meet everyone's needs either.
How long do you want to be comfortable? An hour, two, or all day? That will help define your expectations and help others offer suggestions that better meet your needs.
For reference, the OEM bar end weights cost $13 each from
PartShark and are:
End, Grip (L)
23P-26246-00-00
END, GRIP (R - Throttle side)
23P-26246-00-00
Another $10 for the collars and bolts.
Collar (2 needed)
90387-08089-00
Bolt, Button Head (2 needed)
92014-08060-00