'76,
I'd pick up a copy or Motorcycle Journeys through the Pacific Northwest by Bruce Hanson.
(Amazon) There are lots of amazing roads in that book. The Klickitat loop is one of my favorites. Hitting both ends of the Historic Highway in the Columbia River gorge is a blast, especially when you start in Portland and finish up in The Dalles.
The north end of Hwy 97 in WA is much better than the south IMHO. 97 in Oregon is upland rain shadow desert. You can reach Crater Lake from 97. I've stayed in the cabin/quad/dorm thingy in the park. Very nice. Quiet. Relaxing.
If you're going to be tooling around with time to kill, you might try riding to Hope, BC then heading north on Hwy 1 through the Frazier River Canyon. Hells Gate is a touristy fun thing to do. Turn left at Lytton on to Hwy 12. This road stays high on the valley wall. Rain shadow desert. Get on Hwy 99 in Lillooet. The big gas station with the teal green metal roof is the very last place for fuel until you get to Pemberton. That is my favorite section of road. It is being upgraded to better bridges and the road has been improved a lot since I first road up there. If you do come across a single lane wooden bridge be careful. They are very slick. The Pemberton Lodge is a really nice place to stay without the high prices and attitude of Whistler. Pool. Hot tub. I usually eat at the Wildwood Cafe which is about 3 blocks away on foot. After Pemberton, head south on 99 toward Vancouver. Mind your speed. The road was improved for the Olympics and it's become an autobahn. If you bail out at Horseshoe Bay you can cross over to the island as others have suggested. I've done the road to Tofino, fully loaded, 2-up on my FJR. Ucluelet is a cheaper place to stay. Less touristy but with the same basic services.
Victoria is a pretty place to linger.
You can take the Black Ball ferry (
http://www.cohoferry.com/main/) to Washington. That would put you in Port Angeles. Exit the boat and turn right to loop around the Olympic Peninsula. If you want to ride to the most northern/western point in the continental US head to Neah Bay. I'd grab a hotel in Forks. The Hoh Rain forest is worth stopping at. It's kind of a long grind between Forks and Aberdeen. From Aberdeen you can head toward Seattle on Hwy 12 or continue south toward the Portland metro.
You could ride around Mt St Helens. The back side is a bit bumpy at times, but generally fun. I know a really fun route from Randell, WA to Carson, WA.
Ruggs, OR to Condon, OR is good.
Grants Pass, OR to Crescent City, CA. for Redwood forests. Then take Hwy 36 between Fortuna and Red Bluff, CA for 100 miles of turns. Continue on 36 to Susanville. Head south on 395 to get to Yosemite. ( I took a loop around Lake Tahoe to avoid Reno )
There are lots of fun places to ride out here.