You're not going to hurt anything........ When you do get around to doing the sync make sure that the (R) side TB is turned out 3/4 of a turn from the screwed in bottomed out position (stock). And once this is completed Sync the (L) TB to the newly adjusted (R) side.
Smoother, better, and everyone likes that change.
(L) = clutch lever (R) = front brake lever
(NOTE: 95% + of the Tenere's I have ever worked on have a white paint mark on the (Right) side Throttle body, this is the one to back out 3/4 of a turn. On SOME bikes the white mark is on the (Left) side. This makes no difference, the process is the same. The side with the white paint mark is the side you want to back out 3/4 of a turn and sync the other side)
Like RONH said, I have a Harmonizer and I check mine about every six months. Typically it doesn't need much of a change but im very particular on keeping the engine Tip-Top. NOTE: I have run into one or two bikes that the screw is "loose". These two bikes need to have that screw adjusted really often because it vibrates out I guess? The bike starts to not run that great and he knows the issue. I did the adjustments a few times and showed him the situation and now he adjust it all the time. I think on one of the bikes we had to put a new air screw in and that fixed the issue. This is pretty rare, but just a FYI for anyone else reading this post. Ive recently been seeing bikes out of sync by 35-45 points. Thats a lot, normally they are 10-15. It's not like anything will break or leave you stranded but its a GOOD IDEA to keep an eye on the Sync at least once a year, IMOP...............