RC - As you know, these things are essentially 2 wheel cars and you do stay to the MX schedule so I'd suggest keep on keeping on till there's a reason to suspect a closer look is needed.
I tend to agree, Checkswrecks. I'm a believer that too much maintenance can actually cause more issues than it solves; every time you tear something apart to replace a part that really doesn't need to be replaced, you statistically increase the risk of damaging something else. I'm thoroughly convinced of the reliability of the S10, but I also know that most motorcycles never see anything like the sorts of mileage we put on our cars, and as our bikes approach a milestone of 100,000 miles, it gets tougher to find examples of other bikes that have hit that point and what sorts of failures (if any) these higher mileage bikes have experienced. Mostly I was looking for those weird little consistent idiosyncrasies that plague some bikes but that rarely get encountered because the bikes don't usually reach the sorts of mileages where the problems become observable. It's usually something like a seal in a final drive, or a bearing, or an electronic component; they're fine for a rider who puts 20,000 or 30,000 miles on a bike over its lifetime, but they start to fail with some consistency at maybe 80,000 miles. I guess one example for our particular bike was the CCT on the Gen 1 models.
That was pretty much the gist of my post; to see if there was any sort of
consistent component failure encountered among the guys on here who've gone past the six figure mileage point, so I could address it before it sidelined me while I was in the middle of a trip. I know it's impossible to anticipate every part failure, and even a brand new part can fail, but if say five or six guys with high mileage S10s told me that they had a final drive seal fail after 100,000 miles, that would be something I'd put on my "probably ought to do that sooner than later" list.